Journal of Health Science Research <p>Journal of Health Science Research (JHSR) is an open access international journal publishing original peer-reviewed research articles. The journal is a Bi-annual Publication. The Journal is Indexed in Index Copernicus, Geneva Foundation for Medical Education and Research, i-Scholar, J-Gate Plus, Google Scholar, Genamic Journal Seek, Journal TOC.</p> <div class="headline"> </div> en-US (Editor JHSR) (Paras Sharma) Sun, 01 Jan 2023 00:00:00 +0000 OJS 60 Pyogenic Granuloma of the Oral Cavity: Clinical and Histopathological Features, Etiopathogenesis, and Management <p>Pyogenic granuloma (PG) is a benign vascular tumor that usually occurs on the skin and mucous membranes, mostly of the oral cavity. The most common site for oral PG is the gingiva. The lesion arises in response to various stimuli, such as low-grade local irritation, traumatic injury, or hormonal changes. It may occur at any age, with the highest incidence in the 2<sup>nd</sup> and 5<sup>th</sup> decades of life. Women are more frequently affected due to the increased levels of circulating hormones like estrogen and progesterone. This article reviews the clinical and histopathological features of oral PG, as well as its etiopathogenesis, differential diagnosis, and treatment.</p> Georges Aoun Copyright (c) 2023 Georges Aoun Mon, 26 Dec 2022 00:00:00 +0000 Rectal neuroendocrine tumor, urinary obstruction and bladder calculi <p>Rectal neuroendocrine tumors are rare, represent 12% to 27% of the neuroendocrine neoplasms, often occur in relatively young people, and distant metastases are uncommon. Herein is described the case of an 86-year-old Brazilian man with a rectal neuroendocrine tumor metastasized to the peritoneum, liver, adrenal glands, lungs, bones, and lymph nodes. The huge neoplasm caused compression of the urinary tract, hydronephrosis, and renal failure. Worthy of note was the exceedingly high level of carcinoembryonic antigen (1879 ng/mL). The histopathology and immunohistochemistry data were the base for diagnosis. Case studies of uncommon conditions might contribute to enhancing the awareness and suspicion index of no specialist physicians about this ominous tumor with rising incidence.</p> Vitorino Modesto Santos, Soares VVP, Sartorelli AC, Duarte ML, Garate ALSV Copyright (c) 2023 Vitorino Modesto Santos, Soares VVP, Sartorelli AC, Duarte ML, Garate ALSV Fri, 25 Nov 2022 00:00:00 +0000 A retrospective evaluation of a knee rehabilitation class following evidence-based modifications <p>Knee pain is a common musculoskeletal disorder and contributes a large socio-economic burden to health systems around the world. The traditional strategy to manage knee pain has been exercise. However, there is growing recognition to include coping and self-management educational strategies to improve psychosocial outcomes. <strong>Purpose: </strong>The purpose of this evaluation was to compare the effectiveness of a revised knee rehabilitation class that incorporated an evidence-based educational component (2021-22) to the previous knee rehabilitation class that did not incorporated an evidence-based educational component (2020–21) by comparing pre-class and post-class outcome measurement scores. <strong>Method: </strong>A retrospective evaluation of the knee rehabilitation classes at an NHS Trust in North London, United Kingdom was conducted using the Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lower Extremity Functional Scale (LEFS) from two cohorts of participants from 2020-21 and 2021-22. Data from the two classes were analysed separately and then compared. Satisfaction scores were captured using a questionnaire which participants completed at the end of each class. Data were analysed using the Statistical Software for Excel (XLSTAT) package.<strong> Results: </strong>A total of 46 and 52 patients attended the 2020-21 and 2021-22 classes respectively. Both classes showed significant improvements in KOOS and LEFS when analysed separately, but no significant difference when compared. The 2020-21 class had a mean satisfaction score of 87.2%, and the 2021-22 class had a mean satisfaction score of 91.7%. <strong>Conclusion:</strong> The addition of an evidence-based educational component incorporating coping and self-management strategies in a knee rehabilitation class showed improvement in outcome measurement scores but cannot be considered superior to a class which consisted of an exercise component only.</p> Dr Laran Chetty Copyright (c) 2022 Dr Laran Chetty Fri, 25 Nov 2022 00:00:00 +0000 Anthropogenic Activity and Aquatic Health with References to Hepatotoxicity and Endocrine Disruption in Chrysichyths furcatus <p>Anthropogenic activities had affected aquatic life in the nascent Niger -Delta ecological zone, hence the hepatotoxicity and endocrine disruption in one of the dominant freshwater fish in the zone was investigated. Post juvenile <em>Chrysichthys furcatus</em> of relatively equal sizes and weight (weight of 15.0 ± 0.30 g), body length of 11.40 ± 0.1 cm) were chosen for this investigation. The fish that were purchased from a private fish farm, were acclimatized for 14 days and exposed to the range of concentrations observed in the field (250,500,750) mg/100ml and a control. The water in the aquaria was kept within the standard limit with the aid of aerators. Blood chemistry were determined using standard methods. Physiological responses of the fish exposed to the crude oil were designated based on the severity, good condition and abnormality. The hepatic response indices were affected, and endocrine disruption marker decreased with an increase in the toxicant concentrations. These findings had revealed that crude oil is detrimental to fish health, and there is the tendency of affecting biodiversity and magnification along with the trophic level. It, therefore, becomes imperative that appropriate authorities should take the necessary step to avoid the spillage of oil into the aquatic environment</p> Thomas Ikpesu, Ilesanmi Omotayo Copyright (c) 2022 Thomas Ikpesu, Ilesanmi Omotayo Fri, 25 Nov 2022 00:00:00 +0000 The onset of strabismus complications exemplifies the foremost role of contributing factors associated with the Parental History in children’s <p>The Strabismus instigates irreversible loss of vision if it is not treated properly. The information concerning the responsible factors behind the development of strabismus complications is usually found unclear and less investigated. Such circumstances forced the authors to determine the probable contributing factors associated with the same. The mean age of the children was reported to be 5.2. Among the whole population, 53.4 % of the children’s had the age of 6, while 10.8% and 12.8 % were reported for children’s having the age of 4 and 5 respectively. Data concerning the strabismus complications with special inference on the history, screen time of the patient, outdoor activity/playtime, and visual acuity status information was gained from either subject’s accompanying guardian or parent. The Crosstabulation and Pearson Chi-Square test to find out the link between variables towards the strabismus complications was done by using the MS Office 2019 and SPSS 27.0.0.&nbsp; The link between major complaints found among the participants towards the parental history (X2 = 611.023; df=280; P?&lt;?0.05) has been verified, justifying the prominent role of parental history in developing eye complications in the children under the age of 10. In addition to this, the probable role of playtime, screen time, along with outdoor activity in children with special inference on the strabismus complications has also been verified. The finding of this investigation proposed to represent a candidate that can be used to develop a strategy to diagnose and rectify strabismus incidence in children.</p> Anwer Shakeeb, Naveen H Simon Copyright (c) 2022 Anwer Shakeeb, Naveen H Simon Fri, 25 Nov 2022 00:00:00 +0000